The use of PVC labels in the medical industry, especially for marking instruments that need to withstand numerous cycles of sterilization, is crucial. PVC material is chosen for its durability and resistance to various sterilization methods, including ethylene oxide (EtO) gas sterilization. When applied to medical equipment, PVC labels must withstand high temperatures and harsh chemicals. One critical aspect is the adhesive used for the label. A low-temperature adhesive is often selected for this purpose, as it ensures that the PVC label remains intact during repeated sterilization cycles. This article will explain why PVC labels are ideal for medical applications, their resistance to sterilization processes, and the adhesive considerations necessary for successful use in the healthcare environment.